Mammalian Cell Protein
& Antibody Expression
High-quality CHO and 293-based expression services for antibodies, recombinant proteins, and other complex biologics requiring proper folding, assembly, and post-translational modifications.
What We Offer
VesoBio offers advanced CHO and 293 cell-based protein and antibody expression services for customers seeking reliable, high-yield production of complex biologics. A key advantage of our highly optimized system is that our rapid transient expression delivers exceptional titers with protein quality and consistency that rivals — or perfectly matches — that of stable cell lines. Our workflow supports recombinant antibodies, Fc-fusion proteins, secreted proteins, glycoproteins, cytokines, and other proteins that benefit from mammalian expression systems.
From construct preparation through expression, purification, and fit-for-purpose quality control, we provide a streamlined service model designed to support both rapid project execution and scalable follow-up production with strong downstream usability.
Antibody Expression
Deliver robust CHO and HEK293-based expression for monoclonal antibodies, bispecifics, Fc-fusions, and advanced formats like VHH (nanobodies) and antibody fragments.
Complex Protein Expression
Produce high-fidelity recombinant proteins that demand complex mammalian folding, precise post-translational modifications (PTMs), secretion, or multimeric assembly.
High-Throughput Expression
Execute parallel expression of multiple constructs to accelerate your rapid variant screening, rigorous candidate comparison, and precise lead selection.
Large-Scale Production
Scale your projects with highly optimized CHO expression platforms, delivering large-batch protein and antibody yields to seamlessly support your downstream preclinical needs.
Workflow
Project Review
Assessment of target, construct format, expression goals, timeline, and intended downstream application.
Construct Preparation
Sequence review, expression design, vector preparation, and project-specific optimization strategy.
Transient Expression
Transient transfection and expression in CHO and 293 cells using conditions optimized for protein format and project objectives.
Purification
Purification of expressed protein or antibody using fit-for-purpose workflows based on target format and purity requirements.
QC & Characterization
Quality assessment based on project needs, such as purity analysis, concentration measurement, aggregation profile, and other release criteria.
Final Delivery
Delivery of purified protein together with project summary and applicable QC data package.
Applications
Advance Complex Biologics Expression with CHO
Partner with VesoBio for mammalian cell-based expression of antibodies and recombinant proteins tailored to your research and development needs.
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