VesoBio
Service Platforms
End-to-end capabilities from AI-driven molecular design through to production — accelerating your research from concept to candidate.
- AI Protein Design
- Antibody Discovery
- Protein Expression
- Sequence to BLI Service
- Viral Vectors
- RNA & LNP
- Cell Engineering
AI Protein, Antibody & Mini-Binder Design and Engineering
AI-enabled design and optimization of mini-binders, antibodies, nanobodies, peptides, and recombinant proteins to improve affinity, specificity, stability, solubility, and developability for research and therapeutic applications.
What We Offer
VesoBio provides integrated AI-guided protein engineering services to accelerate the discovery and optimization of biologic candidates. From novel binder design to lead refinement, we combine computational modeling, machine learning-guided optimization, and experimental support to help improve molecular performance and downstream developability.
AI-Guided Molecular Design
Design of novel binders using computational and AI-assisted approaches tailored to target biology and project goals.
Antibody & Nanobody Engineering
Optimization of antibodies and nanobodies for improved binding, specificity, stability, and functional performance.
Mini-Binder Development
Engineering of compact binding proteins and alternative scaffolds for targeted applications requiring high specificity and flexible design.
Affinity & Specificity Optimization
Sequence and structure refinement to enhance target engagement, improve selectivity, and reduce off-target interactions.
Stability & Solubility Improvement
Engineering strategies to improve thermal stability, conformational robustness, solubility, and overall molecular behavior.
Developability Enhancement
Optimization for expression, manufacturability, and downstream usability to support research, preclinical, and translational applications.
Workflow
Target & Project Assessment
Review of target biology, molecular format, project objectives, and desired optimization parameters.
In Silico Design
AI-guided and structure-informed generation of candidate sequences or variant panels for screening and optimization.
Candidate Prioritization
Ranking of candidates based on predicted affinity, specificity, stability, solubility, and developability-related features.
Experimental Validation
Optional expression, screening, and functional characterization of selected candidates to confirm performance.
Iterative Optimization
Further refinement through design-build-test cycles to improve key molecular and biophysical properties.
Lead Delivery
Delivery of optimized candidates and project data packages for downstream research or development.
Applications
Why VesoBio
VesoBio combines AI-enabled design with practical biologics engineering expertise to support efficient molecule optimization across multiple formats. Our flexible workflows are designed to improve both molecular performance and downstream developability, helping customers accelerate programs from concept to candidate.
Advance Your Biologics Program with VesoBio
Partner with VesoBio for AI-guided design and engineering of proteins, antibodies, nanobodies, and mini-binders tailored to your research and development goals.
Request a ConsultationAntibody & Nanobody (VHH) Discovery
Integrated discovery workflows spanning mouse monoclonal antibodies, rabbit polyclonal antibodies, alpaca-derived nanobodies, and in vitro synthetic nanobody library screening to accelerate research, diagnostic, and therapeutic programs.
What We Offer
VesoBio provides integrated antibody and nanobody discovery services to support a broad range of research, diagnostic, and therapeutic development needs. Our platform combines traditional immunization-based antibody generation with advanced in vitro nanobody screening technologies, enabling flexible discovery strategies based on target class, application requirements, and project timelines.
From antigen strategy and binder generation through affinity maturation, epitope mapping, and downstream characterization, we help customers efficiently identify and advance high-quality antibody and nanobody candidates.
Mouse Monoclonal Antibody Discovery
Custom mouse monoclonal antibody discovery for target-specific binder generation, hybridoma screening, and lead clone selection.
Learn MoreRabbit Polyclonal Antibody Generation
Rabbit polyclonal antibody generation for rapid, high-sensitivity antibody production across research and assay development applications.
Learn MoreAlpaca Nanobody (VHH) Discovery
Alpaca immunization-based nanobody discovery workflows for compact, high-affinity VHH lead generation against diverse target classes.
Learn MoreIn Vitro Synthetic Nanobody Library Screening
Animal-free screening of ultra-large synthetic nanobody libraries to identify target-specific VHH binders and accelerate lead discovery.
Learn MoreAccelerate Antibody & Nanobody Discovery
Work with VesoBio to advance mouse monoclonal, rabbit polyclonal, alpaca VHH, and synthetic nanobody discovery through flexible, end-to-end binder identification workflows.
Start Your ProjectProtein Expression & Production
Accelerate your discovery with tailored cell-free and mammalian expression services — optimized for rapid prototyping and scalable production of complex biologics.
What We Offer
VesoBio provides integrated protein and antibody expression solutions designed to accelerate your discovery, screening, and preclinical research.
By uniting robust mammalian (CHO/293) expression for complex biologics with rapid cell-free protein synthesis (CFPS) for high-throughput prototyping, we offer unparalleled flexibility. Whether you are developing standard monoclonal antibodies, specialized nanobodies (VHH), or challenging proteins, our dual-platform approach ensures you have the optimal expression strategy tailored to your timeline, protein complexity, and downstream applications.
Mammalian Cell Protein & Antibody Expression
High-quality CHO and 293-based expression for antibodies, recombinant proteins, and other complex biologics requiring proper folding, assembly, and post-translational modifications.
Learn MoreCell-Free Protein Expression (CFPS)
Accelerate your discovery with rapid in vitro protein expression — designed for fast prototyping, sequence screening, and high-throughput workflows using flexible DNA- or mRNA-templates.
Learn MoreAccelerate Your Protein Expression Program
Partner with VesoBio for tailored mammalian and cell-free expression services optimized for your timeline, protein complexity, and downstream applications.
Request a ConsultationFrom DNA Sequence to BLI Functional Data
AI protein design can generate countless promising sequences — but reliable experimental validation is what turns designs into better models and real candidates.
With VesoBio’s Sequence-to-BLI Service, simply provide your DNA or amino acid sequence, and we handle the rest: codon optimization, gene synthesis, construct preparation, cell-free protein expression, BLI testing, and final data reporting.
Our reliable workflow and functional BLI data help you reduce experimental burden, identify promising candidates faster, and feed high-quality results back into your AI model for quicker optimization and iteration.
From sequence to functional BLI data — faster, easier, and fully integrated.
Key Features
An end-to-end service built for speed, full workflow integration, and decision-ready functional data.
Unmatched Speed
Move from sequence to functional readout in a streamlined workflow designed for rapid turnaround.
Integrated Workflow
One service covers codon optimization, gene synthesis, construct preparation, protein expression, BLI testing, and report generation.
Functional Validation by BLI
Obtain binding and kinetic data to support protein design, binder screening, and candidate prioritization.
Scalable Screening Support
Ideal for evaluating multiple AI-designed protein variants or engineered binder candidates.
Comprehensive Report
Receive a clear, organized report summarizing expression results and BLI testing data.
Service Workflow
Three coordinated stages take your sequence all the way to a final BLI data report.
Gene Synthesis & Construct Preparation
Codon optimization, gene synthesis, and construct preparation.
5 business daysCell-Free Protein Expression
Rapid protein expression using our cell-free platform.
2 business daysBLI Testing & Report
BLI-based binding analysis with a final data report.
3 business daysTypical end-to-end timeline: ~10 business days.
Send Us Your Sequence
Share your DNA or amino acid sequence and project goals — we’ll help you get functional BLI data faster.
Request a QuoteViral Vector Engineering & Production
End-to-end AAV and lentiviral solutions for research and preclinical applications. We streamline your gene delivery programs — from custom capsid and envelope design to scalable manufacturing and rigorous, fit-for-purpose QC.
What We Offer
VesoBio provides integrated viral vector engineering and production services to propel your targeted gene delivery programs from early discovery through preclinical development. Our comprehensive capabilities span AAV capsid engineering, lentiviral surface protein engineering, robust vector packaging, and scalable manufacturing workflows. We specifically design our platforms to enhance tissue tropism, achieve precise targeting, and seamlessly support your downstream research applications.
Whether you require a custom engineering strategy or reliable vector production and quality assessment, we deliver a highly flexible service model tailored to your exact project goals, target biology, and application requirements.
AAV Capsid Engineering
Optimize AAV capsids for enhanced tropism, superior transduction efficiency, and highly precise targeting performance.
Lentiviral Surface Engineering
Customize lentiviral surface proteins to achieve highly selective cell targeting and refined, project-specific tropism.
Tissue-Targeted Vectors
Develop bespoke viral vectors engineered specifically for highly efficient organ- and tissue-specific delivery.
Cell-Specific Vectors
Design and generate precision viral vectors optimized for selective delivery of genetic payloads to strictly defined cell types.
AAV Vector Production
Scale your research with high-titer manufacturing of engineered or standard AAV vectors for robust preclinical studies.
Lentiviral Vector Production
Rely on our efficient packaging and production of engineered or standard lentiviral vectors, customized for your preclinical pipelines.
Workflow
Project Assessment
Review of target tissue or cell type, vector system, engineering objectives, and downstream application requirements.
Engineering Strategy Design
Design of AAV capsid or lentiviral surface engineering approaches based on desired tropism, specificity, and performance goals.
Vector Construction
Generation of engineered vector constructs, capsid variants, or surface protein configurations for evaluation and production.
Packaging & Production
Production of engineered or standard AAV and lentiviral vectors using fit-for-purpose packaging workflows.
QC & Validation
Assessment of vector quality and project-relevant performance parameters, with optional application-specific testing support.
Final Delivery
Delivery of packaged vectors together with supporting QC data and project documentation for downstream research use.
Applications
Typical Deliverables
Why VesoBio
VesoBio combines vector engineering and production into a single integrated workflow to help customers move more efficiently from targeting concept to usable viral vector material. Our service is designed to support both targeted delivery innovation and reliable vector production, with flexibility across AAV and lentiviral systems.
Build Smarter Viral Vectors with VesoBio
Partner with VesoBio for AAV and lentiviral vector engineering and production tailored to your targeting, tropism, and preclinical research goals.
Contact UsRNA Synthesis & Targeted LNP Formulation
Empower your therapeutic pipelines with precision in vivo delivery. We provide a versatile, ligand-directed LNP platform engineered to encapsulate and deliver diverse payloads, fully supported by our custom RNA synthesis and rigorous QC capabilities.
What We Offer
VesoBio provides an advanced, ligand-directed Lipid Nanoparticle (LNP) platform designed to overcome the critical bottlenecks of precise in vivo delivery. While we offer robust, end-to-end capabilities in custom mRNA and circular RNA synthesis, our core strength lies in our adaptable targeted delivery vehicles, engineered to encapsulate a wide range of therapeutic payloads.
To achieve highly selective cell and tissue targeting, we employ advanced conjugation strategies — developing antibody-, nanobody (VHH)-, and peptide-directed LNPs. By seamlessly functionalizing the LNP surface with these precise targeting ligands, we empower you to deliver nucleic acids, gene editing complexes, and other critical modalities directly to the site of action with unprecedented accuracy and efficiency.
mRNA Synthesis
Custom IVT mRNA synthesis for research, gene editing, and RNA therapeutic applications.
Circular RNA Synthesis
Custom circular RNA production for protein-coding or non-coding applications.
LNP Formulation Development
Development of LNP formulations for RNA encapsulation and delivery optimization.
Targeted LNP Development
Engineering of targeted LNPs using antibody, nanobody, peptide, or other ligand-directed strategies.
RNA-LNP Formulation Screening
Screening and optimization of RNA-LNP formulations for delivery performance and candidate selection.
Workflow
Project Assessment
Review of RNA modality, target indication, delivery strategy, intended cell or tissue target, and downstream application goals.
RNA Design & Synthesis Strategy
Definition of RNA construct format, sequence design, modification options, and synthesis workflow based on project requirements.
RNA Production, Purification & QC
Synthesis of mRNA or circular RNA followed by purification and fit-for-purpose analytical quality control.
LNP Formulation Development
Selection and optimization of lipid composition, encapsulation workflow, and formulation parameters for the RNA payload.
Targeted Conjugation & Optimization
Incorporation of targeting ligands and refinement of formulation characteristics to support delivery performance and specificity.
Final Delivery
Delivery of purified RNA, formulated RNA-LNP, or targeted LNP materials together with supporting QC data and project documentation.
Applications
Typical Deliverables
Why VesoBio
VesoBio integrates RNA production and targeted delivery engineering into a single service workflow, helping customers reduce handoff complexity between synthesis, formulation, and targeting design. Our platform is built to support both rapid exploratory work and more advanced preclinical programs requiring customized RNA formats, targeted LNP strategies, and application-oriented QC.
Advance Your RNA Delivery Program with VesoBio
Partner with VesoBio for integrated RNA synthesis, targeted LNP formulation, and delivery engineering tailored to your gene editing and RNA therapeutic goals.
Contact UsCell Line Engineering
Custom cell line engineering services for target validation and assay development, including CRISPR knock-in/knockout, reporter cell line generation, immortalization, and stable cell line development with validated clone delivery and fit-for-purpose QC.
What We Offer
VesoBio provides custom cell line engineering services to support research, target validation, assay development, and preclinical studies. Our integrated workflow covers genome editing, reporter cell line construction, immortalized cell line development, and stable cell line generation, enabling customers to obtain fit-for-purpose cell models tailored to their experimental objectives.
From project design through clone selection and validation, we combine flexible engineering strategies with application-oriented quality control to deliver reliable cell lines for downstream research and development.
CRISPR Knockout & Knock-in
Targeted genome engineering using CRISPR-based strategies for gene knockout, knock-in, and custom genomic modifications.
Reporter Cell Line Generation
Development of reporter cell lines for pathway analysis, target validation, functional screening, and cell-based assay development.
Stable Cell Line Development
Generation of stable expression cell lines for long-term and reproducible studies, including constitutive and customized expression formats.
Cell Immortalization
Engineering of immortalized cell lines to support extended culture, consistent performance, and scalable research applications.
Workflow
Project Assessment
Review of target gene, parental cell line, application goals, engineering strategy, and validation requirements.
Design & Engineering Strategy
Design of CRISPR reagents, donor constructs, reporter cassettes, or immortalization approaches based on project needs.
Cell Engineering
Execution of genome editing, transfection, transduction, selection, or immortalization workflows in the chosen cell background.
Clone Isolation & Expansion
Single-cell cloning or pooled cell enrichment followed by expansion of candidate clones for downstream evaluation.
Validation & QC
Confirmation of editing or expression outcomes through fit-for-purpose molecular and functional assays.
Final Delivery
Delivery of validated pooled cells and/or selected clones, together with supporting QC data and project documentation.
Applications
Why VesoBio
VesoBio offers flexible cell line engineering solutions tailored to diverse research needs, from genome editing to stable and immortalized cell line development. Our service model is designed to support reliable cell model generation, application-oriented validation, and efficient project execution for both discovery and translational workflows.
Build the Right Cell Model for Your Program
Partner with VesoBio for custom cell line engineering services designed for target validation, assay development, and downstream research applications.
Contact Us